Mahboobeh Sheikh
Faculty of Medicine, Zabol university of Medical Sciences, Zabol, Iran
Pouya Ostadrahimi
Faculty of Medicine, Zabol university of Medical Sciences, Zabol, Iran
Abstract
Aim: The aim of this systematic review and the meta-analysis was to evaluate the Prevalence of ASD and VSD in Iranian children with congenital heart defect.
Methods: The proposed protocol and the methods used in this systematic study were developed based on the Cochrane Handbook for Systematic Reviews of Interventions and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Observational studies conducted on the general population are attached and studies on specific populations (acute conditions, home care centers) were excluded.
Results: According to the results of the randomized method (95% CI), the overall ASD prevalence rate among 1260 persons was 8.1%,(95% CI 6.5-9.5) I2 = 77.3 %, the overall VSD prevalence rate among 1100 persons was 27.4%, (95% CI 25-29.7)I2 = 94.4%
Conclusion: To prevent congenital heart disease (CHD), women are advised to start taking multivitamins and folic acid three months before pregnancy and to perform the necessary tests to assess maternal health. If they have diabetes, thyroid disorders, phenylketonuria, infectious diseases, hypertension, etc. they have to undergo appropriate treatment and then plan for pregnancy. In mothers with the above-mentioned diseases or with a history of CHD and chromosomal and genetic diseases in the family and parents, fetal heart echocardiography at 7 weeks of gestation is recommended to diagnose CHD in the fetus.
Key words: Patent ductus arteriosus , Atrial septal defect , congenital heart defectx