Rohan Kalamkar
Assistant Professor, Department of Radiodiagnosis, MIMER Medical College & Dr. BSTR Hospital, Talegaon Station, Tal. Maval. Dist. Pune, 410507. Maharashtra, India
Abstract
Background: Severe microcephaly is often associated with various neurological disorders and developmental delays. Magnetic resonance imaging (MRI) is a non-invasive technique that provides detailed images of brain structure, aiding in the diagnosis of underlying abnormalities.
Aim: To assess the effectiveness of MRI in identifying morphological brain abnormalities in children diagnosed with severe microcephaly.
Methods: This study involved 50 children aged 0-5 years diagnosed with severe microcephaly. Inclusion criteria included confirmed microcephaly (head circumference <3rd percentile); exclusion criteria included significant head trauma and contraindications for MRI. MRI scans were analyzed for structural abnormalities.
Results: MRI revealed structural abnormalities in 80% of the subjects, with cortical malformations being the most common finding.
Conclusion: MRI is a valuable tool for detecting morphological brain abnormalities in children with severe microcephaly, facilitating appropriate clinical management.
Keywords: Magnetic resonance imaging, Microcephaly, Brain abnormalities, Pediatrics, Neurology.