Gaurav Roy
Assistant Professor, Department of ENT, Dr. Ulhas Patil Medical College & Hospital, Jalgaon Kh
Abstract
Background: Laryngeal lesions, including benign and malignant growths, often exhibit alterations in the vascularization of the laryngeal mucosa, a process known as neoangiogenesis. This change plays a crucial role in the growth and progression of both benign and malignant lesions. Narrow Band Imaging (NBI), an advanced endoscopic technique, enhances the visualization of microvascular structures and superficial mucosal changes. This study evaluates the use of NBI in assessing neoangiogenesis in laryngeal lesions.
Methods: A prospective observational study was conducted with 50 patients diagnosed with various laryngeal lesions (benign and malignant) who underwent laryngoscopy with NBI. Vascular patterns observed through NBI were categorized into three types: normal, hypervascular (benign), and neoplastic (malignant). The findings were then compared with histopathological results.
Results: NBI enhanced the visibility of neoangiogenesis in malignant lesions, which displayed irregular, tortuous blood vessels, compared to benign lesions, which showed increased vascular density with regular patterns. Histopathological analysis confirmed that malignant lesions exhibited more pronounced neoangiogenesis. The sensitivity and specificity of NBI for detecting malignant laryngeal lesions were 90% and 85%, respectively.
Conclusion: NBI provides an effective method for endoscopic evaluation of neoangiogenesis in laryngeal lesions, offering enhanced diagnostic accuracy and aiding in treatment planning.
Keywords: Narrow Band Imaging, Neoangiogenesis, Laryngeal Lesions, Endoscopy, Malignant, Benign, Vascularization