Ali Alidadi
Assistant Professor of Nephrology, Department of Nephrology, Zahedan University of Medical Sciences, Zahedan, Iran
Abstract
One of the important reasons for the hospitalization of children in intensive care units is to control and support various organ functions; including the function of the kidneys as highly susceptible organs. Acute kidney failure is not a disease but a complex syndrome in which, besides the kidneys, most body's organs are affected. The aim of this study was to evaluate The Etiology of Acute Renal Failure in the Iranian children.
Methods: The methods used in this systematic review were based on the Checklist (PRISMA) Guidelines. subgroups were analyzed to determine the heterogeneity by participants' age, year of publication, and Province. Finally, a meta-analysis was performed using STATA14 statistical software.
Results: According to the random effect model, the total prevalence of glomerular diseases in 766 acute renal failure patients was 24% (21-27% at a 95% confidence interval, I2 = 96.7%) , the total prevalence of Congenital diseases in 568 acute renal failure patients was 36% (32-39% at a 95% confidence interval, I2 = 98.8%) and the total prevalence of Neurogenic bladder in 253 acute renal failure patients was 17% (13-22% at a 95% confidence interval, I2 = 96.3%).
Conclusion: Early diagnosis of Acute Renal Failure in children slows the progression of the disease and delays the final stage of failure, also considering that hemodialysis and kidney transplantation facilities are often available only for children weighing more than 12-10 kg, diagnosing the early and mysterious symptoms of chronic kidney failure (to prevent the progression of kidney failure as the child grows older, as well as to identify genetic diseases in the family and to prevent the birth of more unhealthy children) is of high significance.
Key words: Acute Renal Failure, Scorpion sting, Pediatric intensive care units, Prevalence