Abstract
This manuscript was prepared as a review presentation of Pemphigus. Pemphigus is a rare skin disease that causes
by autoimmune disorders when body’s defense attacks its own tissues and cells. Patient affected by pemphigus
vulgaris will occasionally present with associated and characteristic nail changes. Article describing pemphigus
vulgaris, it’s complied, reviewed and pertinent information was extracted to provide a concise analysis. The
diagnosis can be made by histologic identification or by presence of IgG and C3 with direct immunofluorescence
testing. Systemic treatment is required and highly effective: It includes a tailored combination of antiinflammatory
medication, immunosuppressive agents or immunomodulatory treatments. The literature on this
topic is still maturing. Here we have the summarized information of rare but sever auto immune disorder i.e.
Pemphigus Vulgaris; its type, symptoms, etiology, pathophysiology, diagnosis, treatment and its after effects or
complications associated with as treatment persist for long duration.
KEYWORDS: Pemphigus Vulgaris, Auto immune disorder, Rituximab.