Sarita Ugemuge
Assistant Professor Dept. of Microbiology Jawaharlal Nehru Medical College, Data Meghe Institute of Medical Sciences Sawangi (Meghe), Wardha
Abstract
Background: Staphylococci have developed resistance to several antibiotics, leaving clinicians with little treatment choices. As a result, reliable drug susceptibility data is critical for a clinician to make an informed clinical decision.
Aims & objectives: To study prevalence of inducible clindamycin resistance (D test) & to assess the frequency of methicillin resistance staphylococci aureus (MRSA).
Material & methods: A total of 85 clinical Staphylococci isolates were obtained from various samples. The Coagulase Test was carried out on a slide. Kirby Bauer Method was used to measure the antimicrobial resistance of the strains collected.
Results: 80 of the 85 Staphylococci isolates were coagulase positive, while only 5 were coagulase negative. Methicillin Resistant Staphylococci (MRSA) made up 14 (17.50%) of the 80 coagulase positive Staphylococci, while Methicillin Sensitive Staphylococcus aureus made up 66 (82.5%). 19 (23.75%) of the 80 isolates of Coagulase-positive Staphylococci were D-test positive, indicating inducible clindamycin resistance. In addition, four of the 19 ICR isolates (05.00 percent) were found to be MRSA.
Conclusion: The organism must be isolated from clinical specimens and its antimicrobial susceptibility pattern studied. It is therefore essential to assess the various factors and methods by which it acquires antimicrobial resistance.
Keywords: staphylococcal isolates, clindamycin resistance, Methicillin resistance