Sunil Kumar Sharma
Department of Pharmacology, Jaipur College of Pharmacy, Jaipur, Rajasthan, India.
Rakesh Sharma
Department of Pharmacology, Jaipur College of Pharmacy, Jaipur, Rajasthan, India.
Abstract
Asthma is associated with inflammation and suffocation of airway wall so patient feel difficulty in breathing and may start tachypnea.Bronchial asthma ic condition in which narrowing of airway due to mucosal edema so patient feel dyspnea and sometime wheezing may occur.
Mast cells present in wall of aveoli have histamine, LT, and PAF mainly in it.while chemoreceptor present in blood that are O2 and Co2 sensitive means if decrease oxygen concentration in blood it send message to brain and increase breathing and tachypnea occur.
Initially we try protect rupture of mast cells present in alveoli to avoid drainage of histamine, LT, and PAF. In acute condition inhalation method is more effective than oral syrup and oral tablets.
Keywords: PAF, LT