Darshana Tote
Associate Professor Dept.of Surgical Oncology Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences Sawangi (Meghe), Wardha
Sagar Gaurkar
Assistant Professor Dept. of Dept.of Surgical Oncology Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences Sawangi (Meghe), Wardha
Abstract
Background: The interconnections between environmental variables and genetics play a crucial role in the development and progression of gastric carcinoma, which is a multifactorial histological altequotientn.
Aim and objective: To determine the correlation between the neutrophil-lymphocyte quotient, the platalet-lymphocyte quotient, and the outcome of gastric carcinoma.
Methodology: Subjects with histopathologically identified stomach carcinoma were included in this prospective trial. The NLR and PLR were estimated using CBC parameters such as neutrophil, lymphocyte, monocyte, white blood cell (WBC), and platelet (Plt) count, as well as hemoglobin (Hb) level. The quotient of absolute neutrophil count to absolute lymphocyte count was defined as NLR, whereas the quotient of absolute platelet count to absolute lymphocyte count was characterized as PLR.
Results: Higher NLR values were shown to be substantially linked with patient age (p value 0.009), histological grade (p value 0.001), and disease stage (p value 0.001). (p value 0.001). The study also discovered that a greater PLR score is connected with a patient's age (p value 0.016), histological grade (p value 0.007), and disease stage (p value 0.007). (p value 0.004).
CONCLUSION: In individuals with stomach carcinoma, hematological markers such as NLR and PLR were linked to prognosis.
Keywords: WBC, Hb,NLR, PLR