Abstract
Background: In the majority of India's urban populations, breast cancer has become the most common type of cancer. A non-invasive imaging method called breast sono-elastography can reveal information about breast lesions.
Aims & objectives: In the current study, we compared the diagnostic efficacy of elastography and histopathology findings of breast lumps.
Material and Methods: The current study involved female patients with solid breast lesions that were sonographically visible and less than 3 cm in size. These lesions were classified as BI RADS 3 and 4 lesions.
Results: 252 female patients had USG elastography during the study period, followed by biopsy or surgery, and histopathology results were made accessible. Histopathologically, 104 (41.72%) of the samples were benign and the remaining 148 (58.73%) were malignant. Age, BIRADS, Elastography Score, and Strain Ratio were all statistically substantially higher in malignant cases compared to benign cases (p 0.001). The majority of benign lesions, according to histopathological diagnosis, were fibroadenomas (77.03%), followed by fibrocystic disease (9.46%), benign fibroepithelial lesions (6.76%), abscesses (5.41%), and sclerosing adenosis (1.35%). While invasive ductal carcinoma (67.31%), invasive mucinous carcinoma (13.46%), invasive poorly differentiated carcinoma (5.77%), ILC (5.77%), medullary carcinoma (1.92%), papillary carcinoma (1.92%), and phylloids (1.92%) made up the bulk of malignant cases.
Combining the Ultrasound Score, Elastography Score, and Strain Ratio resulted in excellent results, with sensitivity, specificity, diagnostic accuracy, NPV, and PPV of 96.00%, 96.05%, 96.03%, 94.12%, and 97.33%, respectively.
Conclusion: The ability to distinguish between benign and malignant breast masses using ultrasound elastography, strain elastography, and ultrasound score has high sensitivity, specificity, and diagnostic accuracy.
Keywords: breast lump, breast malignancy, elastography, histopathology