A Review: Synthesis and Antimicrobial Activity of Novel Heterocyclic Derivatives

Abstract

The antimicrobial activities of newly synthesized compounds were investigated. A diverse set of compounds was synthesized using various synthetic strategies and characterized by spectroscopic methods. The antimicrobial activities of these compounds were assessed against a panel of bacteria and fungi using standard antimicrobial assays such as agar well diffusion and minimum inhibitory concentration. The results demonstrated that several compounds exhibited significant antimicrobial activities against both Gram-positive and Gram-negative bacteria, as well as fungi. Structure-activity relationship studies suggested that specific structural modifications influenced the antimicrobial potency of the compounds. These findings indicate the potential of these novel compounds as effective antimicrobial agents and support further exploration of their therapeutic applications.
Key words: Antimicrobial, Gram-positive & Gram-negative bacteria.