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Kulwinder Kaur
Department of Pharmacy, St. Soldier Institution of Pharmacy, Lidhran Campus, Behind NIT(R.E.C), Jalandhar -Amritsar By Pass Nh-1, Jalandhar 144011, Punjab, India
Rajesh Kumar
Department of Pharmacy, St. Soldier Institution of Pharmacy, Lidhran Campus, Behind NIT(R.E.C), Jalandhar -Amritsar By Pass Nh-1, Jalandhar 144011, Punjab, India
Ajeet Pal Singh
Department of Pharmacy, St. Soldier Institution of Pharmacy, Lidhran Campus, Behind NIT(R.E.C), Jalandhar -Amritsar By Pass Nh-1, Jalandhar 144011, Punjab, India
Amarpal Singh
Department of Pharmacy, St. Soldier Institution of Pharmacy, Lidhran Campus, Behind NIT(R.E.C), Jalandhar -Amritsar By Pass Nh-1, Jalandhar 144011, Punjab, India
Himani Rana
Department of Pharmacy, St. Soldier Institution of Pharmacy, Lidhran Campus, Behind NIT(R.E.C), Jalandhar -Amritsar By Pass Nh-1, Jalandhar 144011, Punjab, India
Abstract
Hyperthyroidism is characterized by excessive secretion of thyroid hormones, leading to elevated serum levels. It affects various organ systems,
including cardiovascular, nervous, gastrointestinal, and hepatic systems. Graves’ disease, an autoimmune condition, is the most common cause, resulting in unopposed stimulation of the thyroid gland by antibodies against the thyroid-stimulating hormone receptor. Surgical removal of the thyroid gland is an option for patients with large glands, severe ophthalmopathy, and lack of remission. Medications like propylthiouracil and methimazole inhibit thyroid hormone secretion by blocking the peroxidase enzyme system and inhibiting coupling reactions. Glucocorticoids are used in thyrotoxicosis with thyroid tissue destruction, such as in subacute thyroiditis or type-2 amiodarone-induced thyrotoxicosis