Evaluation of In-vivo antiulcer activity of Microspheres containing Adina cordifolia extract

Abstract

The administration of Adina cordifolia extract significantly reduced ulcer formation and promoted healing in the treated animal models compared to controls. A notable decrease in ulcer area and depth was observed, accompanied by a reduction in oxidative stress markers and inflammatory responses. The extract demonstrated a protective effect on gastric mucosa, suggesting its potential as a therapeutic agent for ulcer management. Adina cordifolia extract exhibits promising antilucer activity in vivo, indicating its potential for further development as a natural treatment option for ulcer-related conditions. Further studies, including clinical trials, are recommended to confirm its efficacy and safety in human subjects.