Abstract
Background: Acute appendicitis is one of the most common surgical emergencies worldwide, often necessitating an appendicectomy, which can be performed via an open or laparoscopic approach. The laparoscopic appendicectomy has gained popularity due to its minimally invasive nature, offering benefits such as reduced postoperative pain, shorter hospital stays, and quicker return to normal activities. In cases of non-perforated appendicitis, where the appendix has not ruptured, the risk of postoperative complications like surgical site infections (SSIs) is generally lower compared to perforated cases. Approximately 30% of appendectomies are for complicated acute appendicitis (CAA). With laparoscopy, the main post-operative complication is deep abscesses (12% of cases of CAA, versus 4% for open surgery
Aim: The aim of this study is to determine whether the routine administration of postoperative antibiotics is necessary in preventing postoperative complications in patients with non-perforated appendicitis who undergo laparoscopic appendicectomy.Material and Method:
A total of 120 patients with non-perforated appendicitis undergoing laparoscopic appendicectomy divided into two groups. Group B (n=60) patients received single dose of preoperative antibiotic and group A (n=60) patients received preoperative dose, as well as three postoperative doses of antibiotics. patient demographics, comorbidities, preoperative antibiotic use, and operative details. Incidence of SSIs, other complications, hospital stay, readmission, and antibiotic-related adverse effects. Following laparoscopic appendicectomy, surgical wound was inspected after 48 h, 72 h, and on day 7 to look for any signs of postoperative SSI. Group B patients received a single dose of preoperative antibiotics and group A patients received the same regimen, in addition, antibiotics were administered 24 hours postoperatively. Patients of both groups were followed-up for 30 days to
assess the postoperative infectious complications.Results: The mean age in group A was 22.24±6.29 years compared to 25.32±6.55years in group B. No significant difference was observed between the two groups regarding mean age, gender distribution, pain, fever, nausea/vomiting, Mc Burney's tenderness, bowel sounds, total leukocyte count, ultra-sonography, diagnosis, and histopathology report. The difference between both the groups for incidence of SSIs was statistically insignificant. Both groups comprised 120 patients, as well both groups were compared in baseline characteristics. Statistically, there was no significant difference in rates of SSIs between both groups.