Mohammad Hasan Mohammadi
Department of Pediatrics, Zabol University of Medical Sciences, Zabol, Iran
Mehran Hesaraki
Department of Pediatrics, Zabol University of Medical Sciences, Zabol, Iran
Abstract
Introduction:
The acid-base balance plays an important role in maintaining the health of an organism. The concept of acid-base balance signifies the retention of H + concentration homeostasis in body fluids. A slight deviation from the natural values causes severe changes in the rate of chemical reactions of cells, changes that can endanger the life of the organism.
Methods: Searches were conducted by two independent researchers in international (PubMed, Web of science, Scopus and Google scholar) and national (SID, Magiran) data bases for related studies from the inception of the data bases to September 2017 (with out time limitation) in English and Persian languages.
Discussion: Although one of the main causes of fetal acidemia is a decrease in placental-uterine perfusion, several studies have discussed the possible effects of other factors. One of these factors is oxytocin, which is widely used to induce or accelerate the process of labor during labor procedures. Studies on the effects of oxytocin on umbilical cord blood gases have reported controversial findings. Based on the results of See et al study, which was conducted to evaluate the effect of oxytocin administration on umbilical cord blood gases, the mean arterial blood pH was lower in oxytocin-treated patients in comparison with other subjects.
KEY WORDS: Acidemia, fetus, review