Abstract
Background: Surgical site infections (SSIs) represent a significant challenge in modern healthcare, imposing a considerable burden on patient outcomes, healthcare resources, and costs. This study aims to contribute to the existing body of knowledge by analyzing surgical site infections within the context of a tertiary care hospital, with a focus on elucidating the prevalence, distribution across surgical specialties, temporal patterns, and associated risk factors. Methods: A retrospective cross-sectional study was conducted on 1,200 surgical procedures conducted during the specified study period. Data on demographics, surgical procedures, comorbidities, and microbiological findings were collected. Results. During the study period, a total of 1,200 procedures were performed at the hospital. The prevalence of SSI was identified in 8.5% of the cases. Microbiological analysis identified Staphylococcus aureus as the predominant pathogen (45%), followed by Escherichia coli (22%) and Pseudomonas aeruginosa (15%). Statistically, the prevalence of antibiotic-resistant strains, notably the 30% prevalence of MRSA, underscores the ongoing challenge of antimicrobial resistance in the hospital setting. Conclusions: The findings of this study contribute to evidence-based practices for infection control, aiding in the development of tailored interventions to reduce the incidence and improve patient outcomes.